Market Trends of Biopharmaceutical Fermentation Industry
This section covers the major market trends shaping the Biopharmaceutical Fermentation Market according to our research experts:
Chromatography Segment Expects to Register a Significant CAGR Over the Forecast Period
The chromatography segment is expected to witness significant growth in the biopharmaceutical fermentation market over the forecast period. The factors attributing to the segment growth are the growing demand for novel biopharmaceutical drugs coupled with the launch of new products.
The process of chromatography is used to separate molecules according to their sizes, charges, hydrophobicity, and particular ligand binding. Depending on the physical and chemical nature of the fermentation products, the cell-free broth is subjected to the type of chromatography. For instance, the purification of recombinant human insulin and the separation of biological variant insulin molecules from different species is done by reversed-phase high-performance liquid chromatography (HPLC).
The introduction of new devices increases the availability of products in the market which is expected to boost the segment growth. For instance, in October 2021, Thermo Fisher Scientific launched the Thermo Scientific HyPeak Chromatography System. It is one of the first single-use chromatography systems for bioprocessing and offers a wide operational flow range, from 1LPH to 1,980LPH, through a combination of pumps and fluid transfer assemblies (FTA) that enable scalability from process development to cGMP manufacturing. Also, in October 2021, Novasep launched the Hipersep Process M. It is an HPLC chromatography system designed for the purification of pharmaceutical molecules such as peptides, oligonucleotides, insulin, and other synthetic molecules.
Furthermore, the growing technological advancements in chromatography techniques are expected to increase its adoption by the biopharmaceutical industries. This is expected to boost segment growth. For instance, in January 2021, Cytiva further advanced the fiber chromatography technology with the release of Fibro technology-based HiScreen Fibro PrismA. It is one of the newest products available for early monoclonal antibody (mAb) purification process development.
Thus, owing to the aforementioned factors such as the launch of products and advancement in technology, the chromatography segment is expected to project significant growth over the forecast period.
North America is Expected to Dominate the Biopharmaceutical Fermentation Market
North America is expected to witness significant growth in the biopharmaceutical market over the forecast period owing to the factors such as the increasing demand for biotech-based drugs, rising research and development activities, and growing expenditure for the development and advancements in biopharmaceutical fermentation. In addition, the rise in the frequency of chronic diseases rises the consumption of medicines which in turn helps to grow the biopharmaceutical industry and offers growth opportunities for the market players by increasing demand for biologics and biotech drugs which will ultimately propel the utility of biopharmaceutical fermentation.
The rising demand for biopharmaceutical fermentation in the biopharmaceutical sector to reduce the toxicity of drugs and bacterial resistance and increase its efficacy attracts various companies to research and development using biopharmaceutical fermentation. For instance, in August 2022, the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) of the United States granted funding of USD 15.8 million for 14 new technology and workforce development projects that address key opportunities for innovation in the biopharmaceutical sector.
Additionally, the growing prevalence of diseases, such as diabetes, rheumatoid arthritis, and cancer in the region is contributing to the market's growth owing to the use of biopharmaceutical fermentation in manufacturing biotech drugs and biological drugs. For instance, about 32 million and 14 million living in the United States and Mexico were suffering from diabetes in 2021 and this number is projected to reach 36.2 million and 21.8 million by 2045, respectively. Also, as per the 2022 statistics published by ACS, about 1.9 million people living in America were diagnosed with cancer in the United States in 2022. Thus, the high burden of cancer and diabetes among the population raises the demand for effective biological drugs which in turn is anticipated to fuel the market growth over the forecast period.
Furthermore, the rising company focuses on adopting various business strategies such as product launches, approvals, fundraising, and partnerships to expand their offerings in the biopharmaceutical industry are expected to drive the growth of this market. For instance, in February 2022, Kerry Group plc acquired Enmex S.A., an enzyme manufacturer based in Mexico for EUR 62 million. The acquisition accelerates Kerry's innovation capabilities in enzyme engineering, fermentation, and bioprocess development. Also, in September 2021, Thermo Fisher Scientific announced its plan to expand its Nashville, Tenn. site by establishing a dedicated single-use technology manufacturing facility at the site, doubling capacity. The expansion is likely to use bioreactors on a large scale for the manufacturing of biological drugs.
Therefore, owing to the factors such as the high burden of diabetes, and cancer, growing demand for biopharmaceutical fermentation, and rising company activities, the studied market is anticipated to grow over the forecast period.
