Market Trends of Ankylosing Spondylitis Treatment
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Segment is Expected to Hold a Significant Market Share Over the Forecast Period
Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as a first-line drug treatment for Ankylosing Spondylitis (AS). The segment is expected to hold a significant market share owing to the high burden of AS, rising research and development leading to the development of innovative NSAIDs for the treatment. For instance, according to a Statpearls article updated in September 2022, Naproxen is FDA-approved for treating acute gout, ankylosing spondylitis, and other musculoskeletal diseases. According to various research studies, all NSAIDs were significantly more effective in reducing pain severity in AS patients. Therefore, the demand for NSAIDs is high which is expected to augment the segment growth during the forecast period.
Furthermore, the strategic initiatives that market players adopt, such as product launches, approvals, and partnerships, also contribute to the segments' growth. For instance, in April 2022, RINVOQ (upadacitinib) was approved by U.S. FDA as an oral treatment for adults with active ankylosing spondylitis, who have had an inadequate response or intolerance to one or more tumor necrosis factor (TNF) blockers. RINVOQ delivered rapid and meaningful disease control across two pivotal trials.
Additionally, in December 2021, Pfizer received approval from the United States Food and Drug Administration (FDA) for tofacitinib, known as Xeljanz or Xeljanz XR, a new medication to treat ankylosing spondylitis (AS) and other disorders like rheumatoid arthritis, juvenile Idiopathic Arthritis. The approvals of innovative NSAIDs are expected to propel its demand and augment the segment's growth during the forecast period.
North America is Expected to Hold a Significant Market Share Over the Forecast Period
North America is expected to hold a significant market share owing to the high prevalence of target diseases, rising product approvals and launches by market players, and rising government and private organizations reimbursements.
According to an article published in Rheumatology Therapy Journal in December 2021, the prevalence of AS in the United States was 0.2% - 0.5%. The increasing trend of the prevalence of AS in the region is expected to boost the demand for treatment, thereby accelerating market growth.
Furthermore, rising research and development by market players to develop an efficient treatment for ankylosing spondylitis treatment leading to product approvals and launches are expected to propel the market growth. For instance, in December 2021, Coherus Biosciences received the United States Food and Drug Administration (FDA) approval for its Yusimry (adalimumab). It is a tumor necrosis factor (TNF) blocker biosimilar to Humira for treating AS. Also, in July 2022, AbbVie received Health Canada approval for RINVOQ (upadacitinib, 15 mg), an oral, once-daily selective and reversible JAK inhibitor for the treatment of adults with active ankylosing spondylitis (AS). The development and approval of advanced treatments are expected to propel market growth in the region.
In addition, various government and non-profit organizations provide reimbursements or patient assistance for reducing the economic burden of patients undergoing AS treatment. For instance, the Patient Access Network (PAN) Foundation is a US-based non-profit organization that provides USD 5,200 in assistance per year to Ankylosing Spondylitis patients.
Therefore, the North American region is expected to witness growth during the forecast period due to the aforesaid factors such as the high burden of disease, rising product approvals, and launches, and high reimbursements.
