Market Trends of Global Addison's Disease Treatment Industry
Oral Route is Expected to Have the Significant Market Share
The factors propelling the growth of the oral segment are easy to top consume and are better replacement therapy for the disease. The most common oral drugs used for the treatment include corticosteroids such as hydrocortisone, prednisone, or methylprednisone, and fludrocortisone acetate, which replaces the cortisol and aldosterone in the body, which the body lacks to produce. According to the article titled 'Hydrocortisone' published in May 2020, oral hydrocortisone and fludrocortisone are found to have the potential to simulate the physiological serum cortisol level in the body.
In addition, the increasing number of tuberculosis cases is also causing adrenal tuberculosis, leading to adrenal insufficiencies in patients, likely increasing the demand for disease treatment. Adrenal insufficiency also occurs due to direct glandular involvement, extra-adrenal infection, and anti-tuberculosis medication. Moreover, the company focusing on developing oral medications for treating patients with Addison's disease is also likely to increase the market growth over the forecast period. For instance, in February 2022, Diurnal announced that the first patient was dosed in its phase II European clinical trial of modified-release hydrocortisone for treating people with adrenal insufficiency (AI), also known as Addison's disease.
Thus the above-mentioned factors are expected to drive the growth of the studied segment during the te forecast period.
North America is Expected to Have the Significant Market Share
North America is anticipated to have a significant share, owing to the factors such as increasing disease instances in the region, growing demand for new generation technologically integrated advanced therapeutic drugs for swift and long-term therapy, and a well-established healthcare infrastructure.
The increasing number of tuberculosis or adrenal tuberculosis cases causes adrenal insufficiency in patients by destructing the adrenal cortex and hypertrophy of the adrenal glands with caseating granulomas, thus, increasing the demand for better treatment in the region. Adrenal insufficiency also occurs due to direct glandular involvement, extra-adrenal infection, or anti-tuberculosis medication. According to the statistics published by the Centers for Disease Control and Prevention (CDC), in 2021, it has been found that 35.8% of Non-Hispanic Asian persons, 29.7% of Hispanic people, and 11% of Non-Hispanic White people have tuberculosis disease in the United States.
Moreover, the increasing research and development activities and increasing focus of the companies in developing treatments for Addison's disease is further boosting the market's growth in the region. For instance, in January 2022, Antares Pharma announced positive results from a Phase I study for ATRS-1902 for adrenal crisis. ATRS-1902 was developed to treat acute adrenal insufficiency, an adrenal crisis, in adults and adolescents.
Thus the above mentioned factors are expected to drive the growth of the market in this region.
